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TrypanoGEN+ is an international collaborative research network applying an integrated approach to the study of the genetic determinants of two neglected tropical diseases: Human African Trypanosomiasis (HAT) and Schistosomiasis, in Sub-Saharan Africa. TrypanoGEN+ is a continuation of TrypanoGEN that focused only on HAT.




In both HAT and Schistosomiasis, there are populations of individuals that are likely to play a significant role in disease transmission (asymptomatics in HAT and high egg shedders in Schistosomiasis). Our research vision is to provide a fundamental understanding of the host genetic factors and molecular interactions between host and parasite, that lead to these phenotypes as well as investigating the role these populations play in disease transmission and the maintenance of foci of disease.

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