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Publications

Publications arising from the project will be listed here.

Estelle M. Mewamba, Oscar A. Nyangiri, Harry Noyes, Moses Egesa, Encok Matovu, Gustave Simo. Genetics of human schistosomiasis infection intensity and liver disease: a review. Frontiers in Immunology 2021, Volume 12, Article 613468

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Savannah Mwesigwa, Lesedi Williams, Gaone Retshabile, Eric Katagirya, Gerald Mboowa, Busisiwe Mlotshwa, Samuel Kyobe, David P. Kateete, Eddie Mujjwiga Wampande, Misaki Wayengera, Sununguko Wata Mpoloka, Angella N. Mirembe, Ishmael Kasvosve, Koketso Morapedi, Grace P. Kisitu, Adeodata R. Kekitiinwa, Gabriel Anabwani, Moses L. Joloba, Enock Matovu, Julius Mulindwa, Harry Noyes, Gerrit Botha, Collaborative African Genomics Network (CAfGEN), TrypanoGEN Research Group, Chester W. Brown, Graeme Mardon, Mogomotsi Matshaba and Neil A. Hanchard. Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression. The American Journal of Human Genetics 107, 473–486, September 3, 2020 pdf image and link
   
Mulindwa J, Noyes H, Ilboudo H, Pagani L, Nyangiri O, Kimuda MP, Ahouty B, Asina OF, Ofon E, Kamoto K, Kabore JW, Koffi M, Ngoyi DM, Simo G, Chisi J, Sidibe I, Enyaru J, Simuunza M, Alibu P, Jamonneau V, Camara M, Tait A, Hall N, Bucheton B, MacLeod A, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group of the H3Africa Consortium. High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation. The American Journal of Human Genetics 107, 473–486, September 3, 2020 pdf image and link
   
Nyangiri OA, Noyes H, Mulindwa J, Ilboudo H, Kabore JW, Ahouty B, Koffi M, Asina OF, Mumba D, Ofon E, Simo G, Kimuda MP, Enyaru J, Alibu VP, Kamoto K, Chisi J, Simuunza M, Camara M, Sidibe I, MacLeod A, Bucheton B, Hall N, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group, as members of The H3Africa Consortium. Copy number variation in human genomes from three major ethno-linguistic groups in Africa. BMC Genomics (2020) 21:289 pdf image and link
   
Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA; TrypanoGEN Research Group, Rotimi C, Ramsay M; H3Africa Consortium, Adeyemo AA, Lombard Z, Hanchard NA. High-depth African genomes inform human migration and health. Nature | Vol 586 | 29 October 2020 pdf image and link
   

Olivier Fataki Asina, Harry Noyes, Bruno Bucheton, Hamidou Ilboudo, Annette MacLeod, Dieudonne´ Mumba Ngoyi, TrypanoGEN Group, as members of The H3Africa Consortium, SNPs in IL4 and IFNG show no protective associations with human African trypanosomiasis in the DRC. AAS Open Res. 2020; 3: 35

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Ofon E, Noyes H, Ebo'o Eyanga V, Njiokou F, Koffi M, Fogue P, Hertz-Fowler C, MacLeod A, Matovu E, Simo G; TrypanoGEN Research Group, as members of The H3Africa Consortium. Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon. PLoS Negl Trop Dis. 2019 Mar 25;13(3):e0007283. doi: 10.1371/journal.pntd.0007283

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Kaboré JW, Camara O, Ilboudo H, Capewell P, Clucas C, Cooper A, Kaboré J, Camara M, Jamonneau V, Hertz-Fowler C, Bélem AMG, Matovu E, Macleod A, Sidibé I, Noyes H, Bucheton B; TrypanoGEN Research Group, as member of the H3Africa Consortium. Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population. Infect Genet Evol. 2019 Jul;71:108-115. doi: 10.1016/j.meegid.2019.03.021. Epub 2019 Mar 23.        

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Kamoto K, Noyes H, Nambala P, Senga E, Musaya-Mwalija J,  Kumwenda B, Bucheton B,  Macleod A,Herz-Fowler C,  Matovu E, Chisi JE. TrypanoGEN Research Group, as member of the H3Africa Consortium. Association of APOL1 renal disease risk alleles with Trypanosoma brucei rhodesiense infection outcomes in the Northern part of Malawi. 2019. PLoS Negl Trop Dis 13:2019 e0007603

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Nyangiri OA, Noyes H, Mulindwa J, Ilboudo H, Kabore JW, Ahouty B, Koffi M, Asina OF, Mumba D, Ofon E, Simo G, Kimuda MP, Enyaru J, Alibu VP, Kamoto K, Chisi J, Simuunza M, Camara M, Sidibe I, MacLeod A, Bucheton B, Hall N, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group, as members of The H3Africa Consortium. BMC Genomics. 2020 Apr 10;21(1):289. doi: 10.1186/s12864-020-6669-y. PMID: 32272904 

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Ofon E, Noyes H, Ebo'o Eyanga V, Njiokou F, Koffi M, Fogue P, Hertz-Fowler C, MacLeod A, Matovu E, Simo G; TrypanoGEN Research Group, as members of The H3Africa Consortium. Association between IL1 gene polymorphism and human African trypanosomiasis in populations of sleeping sickness foci of southern Cameroon. PLoS Negl Trop Dis. 2019 Mar 25;13(3):e0007283. doi: 10.1371/journal.pntd.0007283.   
   
Kaboré JW, Camara O, Ilboudo H, Capewell P, Clucas C, Cooper A, Kaboré J, Camara M, Jamonneau V, Hertz-Fowler C, Bélem AMG, Matovu E, Macleod A, Sidibé I, Noyes H, Bucheton B; TrypanoGEN Research Group, as member of the H3Africa Consortium. Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population. Infect Genet Evol. 2019 Jul;71:108-115. doi: 10.1016/j.meegid.2019.03.021. Epub 2019 Mar 23.  
   
Kamoto K, Noyes H, Nambala P, Senga E, Musaya-Mwalija J,  Kumwenda B, Bucheton B,  Macleod A,Herz-Fowler C,  Matovu E, Chisi JE.TrypanoGEN Research Group, as member of the H3Africa Consortium. Association of HLAGwith Trypanosoma brucei rhodesienseinfection outcomes in the Northern part of Malawi. 2019. In Press  
   
Ofon, E., Noyes, H., Mulindwa, J., Ilboudo, H., Simuunza, M., Eboo, V., et al. (2017). A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations.PLoS Neglected Tropical Diseases, 11(10), e0005979. http://doi.org/10.1371/journal.pntd.0005979 pdf image and link
   
Kimuda, M. P., Noyes, H., Mulindwa, J., Enyaru, J., Alibu, V. P., Sidibe, I., et al. (2018). No evidence for association between APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations. PLoS Neglected Tropical Diseases, 12(2), e0006300–10. http://doi.org/10.1371/journal.pntd.0006300 pdf image and link
   
Mulindwa, J., Noyes, H. A., Ilboudo, H., Nyangiri, O., Koffi, M., Mumba, D., et al. (2017). Genomic evidence for population specific selection in Nilo-Saharan and Niger-Congo linguistic groups in Africa, 1–30. http://doi.org/10.1101/186700 bioarchive image and link
   
Ahouty, B., Koffi, M., Ilboudo, H., Simo, G., Matovu, E., Mulindwa, J., et al. (2017). Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d'Ivoire, 1–22. http://doi.org/10.1101/186718 bioarchive image and link
   
Capewell, P., Bucheton, B., Clucas, C., Ilboudo, H., Cooper, A., Gorman, T.-A., et al. (2017). T cell activation and the HLA locus associate with latent infections of human African trypanosomiasis 1–25. http://doi.org/10.1101/184762 bioarchive image and link
   
Kabore, J. W., Ilboudo, H., Noyes, H., Camara, O., Kaboré, J., Camara, M., et al. (2017). Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea. PLoS Neglected Tropical Diseases, 11(8), e0005833. http://doi.org/10.1371/journal.pntd.0005833 pdf image and link
   
Cooper, A., Ilboudo, H., Alibu, V. P., Ravel, S., Enyaru, J., Weir, W., et al. (2017). APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis. eLife, 6, 56. http://doi.org/10.7554/eLife.25461 pdf image and link
 
Ilboudo, H., Noyes, H., Mulindwa, J., Kimuda, M. P., Koffi, M., Kabore, J. W., et al. (2017). Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis. PLoS Neglected Tropical Diseases, 11(6), e0005438. pdf image and link

 

 
 
 
 
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